Aesthera vs Fuse Health: Peptides or a Full Aesthetic Menu?
Fuse Health sells peptides, GLP-1 and longevity from $699 a month. Aesthera sells six aesthetic programmes, including hair loss, testosterone and skin and aging, for $497 a month. Fuse is the more focused product, and Aesthera is the broader one.
Fuse Health is a peptide company, and it does not pretend otherwise. The word peptide is in its headline, its pricing page and its positioning.
The menus do not overlap much
This is the whole comparison in one table.
| Programme | Fuse Health | Aesthera |
|---|---|---|
| Peptides | Yes, the core offer | Yes |
| GLP-1 and weight management | Yes | Yes |
| Longevity | Yes | Covered through skin and aging |
| Hair loss | No | Yes |
| Testosterone therapy | No | Yes |
| HRT for women | No | Yes |
| Skin and aging | No | Yes |
Four rows in that table are blank for Fuse. If those four are what you want to sell, the comparison is over before price comes into it.
What Fuse publishes that most platforms do not
Credit where it is due: Fuse puts numbers on its own site that its competitors leave out.
- 1,200+ programmes launched.
- 94% refill retention.
- Under 24 hours average provider review.
- 50+ operators already running peptide brands on it.
Most platforms here publish nothing comparable. That is worth acknowledging, and refill retention is the number to interrogate hardest, because it depends on how the cohort was defined and on whether churned patients left. Ask how it is measured.
Where the extra $202 a month goes
Fuse's Growth tier is $699. Aesthera is $497. The difference is $202 a month.
For that you get a full CRM, sequences and automations inside the platform, and a branded storefront and portal. If you would otherwise buy a CRM and an email tool separately, that is real value and the difference may be a saving rather than a cost.
Fuse's Partner tier is $3,000 a month, which adds a dedicated client success manager, affiliate portals, a GoHighLevel integration and SDK access. That tier is aimed at established brands, not at a single med spa.
Med spas are one of six audiences
Fuse names med spas alongside coaches and educators, fitness and wellness brands, influencers and creators, e-commerce brands, and health and fitness apps.
That is a deliberate choice and a defensible one for them. It does mean the intake, onboarding and support paths are built to serve all six, and a med spa is one of them rather than the only one.
Why med spas sell peptides at all
Peptides are a natural fit for a med spa because they are prescribed, they recur, and the patient is already sitting in front of you.
Unlike a single treatment, a peptide protocol runs for months. That makes it a subscription rather than a transaction, and subscriptions are what make a clinic's revenue predictable.
They also suit the aesthetic patient. Someone already buying skin treatments is a plausible buyer for a longevity or recovery protocol, which is not true of every prescription category.
That is the case for Fuse's focus. If peptides are what you intend to sell, a platform built entirely around them is not a limitation.
What the included CRM is actually worth
Fuse includes a full CRM, sequences and automations from $699. Aesthera does not include a CRM, and that is the most concrete thing the extra $202 buys.
Price the alternative honestly. A med spa buying a standalone CRM and email tool separately is looking at a monthly cost that can approach or exceed the difference, plus the integration work.
Two questions decide it. Does the included CRM cover what you need, and is the data yours if you leave? A CRM that cannot export its contact history is a lock-in dressed as a feature.
How 50-state coverage actually works
Fuse states providers in 50 states, and most platforms here make a similar claim.
Coverage is not a switch. It depends on having clinicians licensed in each state and a pharmacy that can ship there. A vendor can hold a licence in a state and still be slow to staff it.
Ask for the states you actually sell in by name, and ask what the average time to a provider review is in those states specifically. Fuse publishes an average under 24 hours. Averages hide the slow states, and the slow states are the ones your patients live in.
A worked first year on Fuse Growth
Fuse Growth is $699 a month with no setup fee stated. That is $8,388 in year one.
Aesthera is $497 a month plus a $997 setup: $6,961 in year one, then $5,964 a year after.
Fuse Growth at $699 a month is $8,388 a year with no setup stated. Fuse costs $1,427 more in year one and $2,424 more every year after. Set that against what a CRM and the automation would cost you separately. If they would cost more than $2,424, Fuse is the cheaper way to get them.
If it comes in below, Fuse's premium is the price of a peptide-specialist platform with a CRM included. Whether that is worth $2,424 depends on whether you would otherwise buy a CRM.
What happens when a patient order fails
Every platform ships prescriptions, and every platform occasionally ships one wrong, late or not at all.
The question is who the patient contacts and who fixes it. Ask any vendor three things: is there a patient-facing support line, how is the med spa notified of a failure, and who replaces the order at whose cost.
On a platform with 400 brands the answer may be a ticket queue. On a smaller platform it may be a named contact. Neither is automatically better, but knowing which you are buying matters more than the monthly fee difference.
Interrogating the refill retention figure
Fuse publishes 94% refill retention, and that is the most consequential number on its site.
Retention measures whether patients keep buying. A high figure means refills recur, and recurring refills are what make a prescription programme worth running.
Ask how the cohort is defined. Is it patients who reached their first refill, or all patients who started? Does it count a patient who paused for two months and returned? A figure measured from first refill onwards will always look better than one measured from signup.
This is not an accusation. It is the difference between a metric and a claim, and it is one question long to resolve.
Which should a med spa choose?
If peptides are the product and you want a CRM and automation included, Fuse is a focused answer with good documentation. Its published retention figure is the kind of claim most vendors avoid.
If you want to sell hair loss, hormone therapy or skin and aging alongside peptides, Aesthera is the only one of the two that offers them. The $202 a month you save is a secondary reason.
Does Fuse Health offer hair loss or testosterone programmes?
No. Fuse's stated menu is peptides, GLP-1 and longevity. Aesthera adds hair loss, testosterone therapy, HRT for women and skin and aging.
How much does Fuse Health cost?
Growth is $699 per month and Partner is $3,000 per month, with no setup fee stated. Published on its own site on 19 September 2026.
Is Fuse Health's 94% refill retention figure reliable?
It is Fuse's own published figure. Ask how the cohort was defined and whether churned patients are excluded before you rely on it.
Does Fuse Health include a CRM?
Yes. The Growth tier includes a full CRM, sequences and automations, plus a branded storefront and portal with wholesale pricing on every order.
Which is cheaper, Aesthera or Fuse Health?
Aesthera is $497 per month flat and Fuse Growth is $699. If you would otherwise buy a CRM and email tool separately, Fuse's price may be a saving rather than a premium.
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